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Transforaminal vs Posterior Lumbar Interbody Fusion For Symptomatic Single-Level Spondylolisthesis

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Ace Report Cover
November 2025

Transforaminal vs Posterior Lumbar Interbody Fusion For Symptomatic Single-Level Spondylolisthesis

Vol: 307| Issue: 11| Number:8| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Transforaminal versus posterior lumbar interbody fusion for symptomatic single-level spondylolisthesis (LIFT): a multicentre controlled, patient blinded, randomised non-inferiority trial.

Lancet Reg Health Eur . 2024 Jun 19:43:100964.

Contributing Authors:
IJMH Caelers R Droeghaag SL de Kunder J Most K Rijkers RHMA Bartels JMA Kuijlen MHHM Hulsbosch WLW van Hemert RA de Bie H van Santbrink

Synopsis

One hundred fifty eight patients with symptomatic single-level (degenerative, isthmic, or iatrogenic) spondylolisthesis were randomized 1:1 to TLIF (n=78) or PLIF (n=80). The primary outcome was change in ODI from baseline to 12 months. Secondary outcomes included QALYs (EQ-5D-5L, SF-36), back/leg pain (NRS), anxiety/depression (HADS), peri-operative blood loss, operative time, length of stay, and...

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