LOGIN
Intrathecal Fentanyl Reduces Postoperative Opioid Use After Lower-Extremity Orthopedic Surgery
October 2025
Intrathecal Fentanyl Reduces Postoperative Opioid Use After Lower-Extremity Orthopedic Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The effects of intrathecal fentanyl on postoperative opioid utilization rates in elderly patients undergoing lower extremity orthopedic surgery: a randomized controlled trial.
Perioper Med (Lond) . 2025 May 19;14(1):58.Synopsis
One hundred eighty elderly patients scheduled for lower-extremity orthopedic procedures were randomized to bupivacaine + fentanyl 25 µg (BF1, n=77), bupivacaine + fentanyl 50 µg (BF2, n=77), or bupivacaine alone (B, n=37). The primary outcome was opioid use rate; secondary outcomes included NRS pain (≥4) and overall analgesic use on POD1–3. Outcomes were assessed daily to POD3. Overall, the result...
To view the full content, login to your account,
or start your 30-day FREE Trial today.
FREE TRIAL
LOGIN
Forgot Password?
Explore some of our unlocked ACE Reports below!
Learn about our AI Driven
High Impact Search Feature
Our AI driven High Impact metric calculates the impact an article will have by considering both the publishing journal and the content of the article itself. Built using the latest advances in natural language processing, OE High Impact predicts an article’s future number of citations better than impact factor alone.
Continue
Join the Conversation
Please Login or Join to leave comments.