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Corticosteroid + Hyaluronic Acid Injection for Thumb-Base Osteoarthritis: Short-Term Pain Benefit
October 2025
Corticosteroid + Hyaluronic Acid Injection for Thumb-Base Osteoarthritis: Short-Term Pain Benefit
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Improvement of rhizarthrosis pain management with the infiltration of hyaluronic acid and corticosteroids versus corticosteroids alone.
Joint Bone Spine . 2025 Jul;92(4):105849.Synopsis
One hundred fifty patients with symptomatic rhizarthrosis were randomized to receive a single ultrasound-guided intra-articular injection of corticosteroid (CS) + intra-articular hyaluronic acid (HA) (n=73) or CS+saline (n=76). The primary outcome was change in activity-related thumb pain (0–10 VAS) at 3 months (M3). Secondary outcomes included VAS at activity and rest at M1/M6/M12, Cochin hand fu...
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