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Night Orthosis Aids PIP Recovery After Collagenase Clostridium Histolyticum for Dupuytren’s

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Ace Report Cover
October 2025

Night Orthosis Aids PIP Recovery After Collagenase Clostridium Histolyticum for Dupuytren’s

Vol: 307| Issue: 10| Number:106| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Clinical Effectiveness of an Orthosis After Collagenase Clostridium Histolyticum Injection for Dupuytren Contracture.

J Hand Surg Am . 2025 May;50(5):547-553.

Contributing Authors:
C Dent N Coutelle M Gill P Simon M Doarn J Nydick

Synopsis

Seventy-nine patients with Dupuytren contracture were randomized to receive a nighttime extension orthosis after collagenase clostridium histolyticum (CCH) (n=39) or no orthosis (n=40). The primary outcome of interest was residual flexion contracture (degrees) at follow-up. Secondary outcomes included QuickDASH and orthosis compliance; adverse events and skin tears were recorded. Outcomes were as...

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