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Effects Of Oral Clonidine On Bleeding In Pelvic And Acetabular Fractures Surgery
October 2025
Effects Of Oral Clonidine On Bleeding In Pelvic And Acetabular Fractures Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effects of oral clonidine on bleeding in pelvic and acetabular fractures surgery: a randomized controlled trial.
BMC Musculoskelet Disord . 2025 Apr 21;26(1):384.Synopsis
Eighty-nine patients with pelvic or acetabular fractures were randomized to receive oral clonidine 200 mcg 75–90 min pre-anesthesia (n=45) or placebo (n=44). The primary outcome of interest was blood loss (intra- and postoperative, including hidden loss). Secondary outcomes of interest included postoperative pain (VAS), surgeon-rated visual field quality, hemoglobin (preop, postoperative day 1 and...
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