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Evaluation of the Role of PRP in Acute Tibial Shaft Fractures Fixation With Intramedullary Nailing
October 2025
Evaluation of the Role of PRP in Acute Tibial Shaft Fractures Fixation With Intramedullary Nailing
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Evaluation of the Role of PRP in Acute Tibial Shaft Fractures Fixation With IM Nail: A Double-Blinded Randomized Controlled Trial.
Adv Orthop . 2025 Apr 7:2025:5642601.Synopsis
Thirty-two patients with acute AO 42-C3 tibial shaft fractures were randomized to receive platelet-rich plasma (PRP) injected at the fracture site after Intramedullary (IM) nailing (n=16) or a normal saline injection (n=16). The primary outcome was cortex-to-callus ratio on serial radiographs. Secondary outcomes included time to union and patient-reported measures (SF-36, EQ-5D-3L, VAS pain). Outc...
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