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Efficacy Of Two Doses Of Intra-Articular Ozone Therapy For Pain And Functional Mobility In Knee OA
October 2025
Efficacy Of Two Doses Of Intra-Articular Ozone Therapy For Pain And Functional Mobility In Knee OA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of two doses of intra-articular ozone therapy for pain and functional mobility in knee osteoarthritis: a double-blind randomized trial.
Adv Rheumatol. 2025 01-Mar;():. 10.1186/s42358-025-00443-wSynopsis
Sixty patients with primary knee osteoarthritis were randomized to receive intra-articular ozone therapy at 40 µg/mL (n=20), 20 µg/mL (n=20), or oxygen as control (n=20). The primary outcome was pain reduction, measured by the Visual Analog Scale (VAS) and WOMAC pain subscale. Secondary outcomes included functional mobility (WOMAC function, FROM, TUG, and 6MWT). Outcomes were evaluated at baseline...
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