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Liposomal vs Standard Bupivacaine in Supraclavicular Plexus Block
April 2025
Liposomal vs Standard Bupivacaine in Supraclavicular Plexus Block
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Addition of Liposomal Bupivacaine to Standard Bupivacaine versus Standard Bupivacaine Alone in the Supraclavicular Brachial Plexus Block: A Randomized Controlled Trial.
Anesthesiology . 2024 Oct 1;141(4):732-744.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty patients undergoing distal radial fracture fixation were randomized to receive either a supraclavicular brachial plexus block with 10 ml 0.5% bupivacaine plus 10 ml 1.33% liposomal bupivacaine (n=40), or 20 ml 0.5% bupivacaine alone (n=40). The primary outcome was the weighted area under the curve (AUC) of numerical pain rating scores at rest over the first 48 hours postoperatively. Seconda...
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