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Epidural Dexamethasone + B12 Improves Early Recovery After PEID
September 2025
Epidural Dexamethasone + B12 Improves Early Recovery After PEID
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial.
J Orthop Surg Res . 2024 Nov 7;19(1):733.Synopsis
Fifty-six patients with lumbar disc herniation were randomized to receive percutaneous endoscopic interlaminar discectomy (PEID) plus epidural dexamethasone (15 mg) + vitamin B12 (1 mg) (combined treatment; n=28) or PEID plus epidural saline (single surgery; n=28). The primary outcome was pain (VAS for low back and leg) at prespecified time points. Secondary outcomes included JOA, ODI, serum TNF-α...
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