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Magnesium Sulfate Effect on the Peripheral Analgesic Cocktail in Total Knee Arthroplasty
January 2025
Magnesium Sulfate Effect on the Peripheral Analgesic Cocktail in Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Magnesium sulfate enhances the effect of the peripheral analgesic cocktail in total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials.
EFORT Open Rev . 2024 Sep 2;9(9):896-907.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
This systematic review and meta-analysis included five randomized controlled trials with 432 patients undergoing total knee arthroplasty. It compared the addition of magnesium sulfate to peripheral analgesic cocktails versus standard cocktails alone. Outcomes of interest included postoperative pain scores (VAS), opioid consumption, time to rescue analgesia, range of motion, mobilization distance, ...
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