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Erythromycin- and Colistin-Loaded Cement for Infection in Total Knee Arthoplasty
December 2024
Erythromycin- and Colistin-Loaded Cement for Infection in Total Knee Arthoplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The Use of Erythromycin and Colistin Cement in Total Knee Arthroplasty Does Not Reduce the Incidence of Infection: A Randomized Study in 2,893 Knees With a 9-year Average Follow-Up.
J Arthroplasty. 2024 01-Sep;():. 10.1016/j.arth.2024.04.039Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Two thousand eight hundred ninety-three knees from patients undergoing primary total knee arthroplasty were randomized to receive plain bone cement (n=1,452) or erythromycin and colistin-loaded bone cement (n=1,441). The primary outcome of interest was the rate of deep prosthetic joint infection. Secondary outcomes included rates of aseptic loosening and antibiotic resistance in infecting organism...
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