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Ketamine + Epidural Morphine for Postoperative Analgesia After Lumbar Laminectomy or Discectomy

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Ace Report Cover
December 2024

Ketamine + Epidural Morphine for Postoperative Analgesia After Lumbar Laminectomy or Discectomy

Vol: 306| Issue: 12| Number:49| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Adding Ketamine to Epidural Morphine Does Not Prolong Postoperative Analgesia After Lumbar Laminectomy or Discectomy.

J Neurosurg Anesthesiol . 2024 Jul 1;36(3):244-251.

Contributing Authors:
P Prabhakar R Mariappan RK Moorthy BR Nair R Karuppusami KR Lionel

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Synopsis

Forty-eight patients undergoing lumbar laminectomy or discectomy were randomized to receive either epidural morphine alone (n=24) or epidural morphine with ketamine (n=24). The primary outcome was the duration of analgesia, measured as the time to the first postoperative analgesic request. Secondary outcomes included pain scores at rest and movement, systemic hemodynamics, and the incidence of sid...

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