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Gabapentin vs Pregabalin as a Prodrug in Pain Control post Orthopedic Surgery on the Upper Limb
March 2025
Gabapentin vs Pregabalin as a Prodrug in Pain Control post Orthopedic Surgery on the Upper Limb
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The Effect of Oral Gabapentin and Pregabalin as a Prodrug in Pain Control after Orthopedic Surgery on the Upper Limb: A Double-Blind Parallel Randomized Clinical Trial Study.
Anesthesiol Res Pract. 2024 May 6:2024:7193599.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy-four patients undergoing elective upper limb orthopedic surgery were randomized to receive either oral pregabalin 150 mg (n=37) one hour before surgery or oral gabapentin 300 mg (n=37) two hours before surgery. The primary outcome was postoperative pain intensity assessed by visual analog scale (VAS). Secondary outcomes included pain scores at different time points (preoperative, PACU, 6 h...
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