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NSAID and Anti-TNF Therapy vs Anti-TNF Therapy on the Spine in Patients with Axial Spondyloarthritis
January 2025
NSAID and Anti-TNF Therapy vs Anti-TNF Therapy on the Spine in Patients with Axial Spondyloarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparison of the effect of treatment with NSAIDs added to anti-TNF therapy versus anti-TNF therapy alone on the progression of structural damage in the spine over 2 years in patients with radiographic axial spondyloarthritis from the randomised-controlled CONSUL trial
Ann Rheum Dis . 2024 Apr 11;83(5):599-607.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred and nine patients with radiographic axial spondyloarthritis (r-axSpA) were randomized to receive combination therapy with golimumab and celecoxib (n=54) or golimumab monotherapy (n=55). The primary outcome was the change in radiographic spinal progression as measured by the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) over two years. Secondary outcomes included syndesmop...
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