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Methylprednisolone and Tranexamic Acid Use in Total Hip Arthroplasty for Accelerated Recovery
June 2025
Methylprednisolone and Tranexamic Acid Use in Total Hip Arthroplasty for Accelerated Recovery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Clinical utilization of methylprednisolone in conjunction with tranexamic acid for accelerated rehabilitation in total hip arthroplasty.
J Orthop Surg Res. 2023 Oct 4;18(1):747.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty patients undergoing primary total hip arthroplasty were randomized to receive either tranexamic acid alone (n=40) or tranexamic acid combined with methylprednisolone (n=40). The primary outcomes were levels of CRP and IL-6 as markers of inflammation. Secondary outcomes included pain (VAS scores), use of analgesics, nausea and vomiting (PONV), blood glucose fluctuations, fatigue (ICFS), rang...
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