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2-Octyl vs n-Butyl Cyanoacrylate for Ankle Fracture Wound Closure
September 2025
2-Octyl vs n-Butyl Cyanoacrylate for Ankle Fracture Wound Closure
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparison of 2-octyl cyanoacrylate and n-octyl cyanoacrylate topical skin adhesives for wound closure after ankle fracture surgery: a prospective randomized trial.
Sci Rep . 2023 Oct 10;13(1):17099.Synopsis
Fifty-six patients with lateral malleolar (rotational ankle) fractures were randomized to receive 2-octyl cyanoacrylate (n=27) or n-butyl (90% n-butyl/10% 2-octyl) cyanoacrylate (n=28) for skin closure after standardized plate fixation; fifty-five completed follow-up. The primary outcome was cosmetic appearance by HWES at three and six months. Secondary outcomes included patient satisfaction with ...
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