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Acupuncture vs. Celecoxib for Knee Osteoarthritis: A Randomized fMRI Study on Pain Modulation
February 2025
Acupuncture vs. Celecoxib for Knee Osteoarthritis: A Randomized fMRI Study on Pain Modulation
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Modulation effects of different treatments on periaqueductal gray resting state functional connectivity in knee osteoarthritis knee pain patients.
CNS Neurosci Ther . 2023 Jul;29(7):1965-1980.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred eighty (180) patients with knee osteoarthritis (KOA) knee pain were randomized into five groups: verum acupuncture (VA, n=36), sham acupuncture (SA, n=36), celecoxib (SC, n=36), placebo (PB, n=36), and waiting list (WT, n=36). Additionally, 41 healthy controls (HCs) were included. Patients in the VA and SA groups received 10 acupuncture sessions over two weeks, while the SC group recei...
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