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Synergistic Effect of Metamizole w/ Paracetamol & NSAIDs in Arthroscopic Shoulder Surgery

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Ace Report Cover
April 2023

Synergistic Effect of Metamizole w/ Paracetamol & NSAIDs in Arthroscopic Shoulder Surgery

Vol: 303| Issue: 4| Number:8| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Additive or synergistic analgesic effect of metamizole on standard pain treatment at home after arthroscopic shoulder surgery: A randomised controlled superiority trial.

Eur J Anaesthesiol. 2023 Mar 1;40(3): 171-178.

Contributing Authors:
B Stessel M Lambrechts S Evers C Vanderstappen I Callebaut JP Ory J Herbots I Dreesen M Vaninbroukx M Van de Velde

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Synopsis

One hundred and ten patients undergoing elective ambulatory arthroscopic shoulder surgery were randomized to receive triple therapy with oral metamizole, paracetamol, and ibuprofen (n=55) or paracetamol and ibuprofen only (n=55). The primary outcome of interest was post-operative pain intensity during movement on a Numeric Rating Scale (NRS) on post-operative day 1. Secondary outcomes of interest ...

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