AAOS 2023: Oral Versus Intravenous Tranexamic Acid for Primary Total Hip or Knee Arthroplasty
AAOS 2023: Oral Versus Intravenous Tranexamic Acid for Primary Total Hip or Knee Arthroplasty
Comparing the Effectiveness of Oral versus Intravenous Tranexamic Acid in Primary Total Hip and Knee Arthroplasty: A Randomized Trial
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Synopsis
Four hundred patients undergoing total knee arthroplasty (TKA; n=200) or total hip arthroplasty (THA; n=200) were randomized to receive either oral (n=200) versus intravenous (IV) tranexamic acid (TXA) (n=200) preoperatively. Patients were randomized using a 1:1 block size within each surgery group. The primary outcome of this trial was calculated blood loss (CBL) based on the hematocrit levels on...
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