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High Loading Dose & Daily High and Low Dose Vitamin D3 Supplementation on Acute Fracture Healing

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Ace Report Cover
March 2023

High Loading Dose & Daily High and Low Dose Vitamin D3 Supplementation on Acute Fracture Healing

Vol: 303| Issue: 3| Number:21| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effect of Vitamin D(3) Supplementation on Acute Fracture Healing: A Phase II Screening Randomized Double-Blind Controlled Trial.

JBMR Plus. 2022 Dec 22;7(1):e10705.

Contributing Authors:
GP Slobogean S Bzovsky NN O'Hara LS Marchand ZD Hannan HK Demyanovich DW Connelly JD Adachi L Thabane S Sprague

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Synopsis

One hundred and two patients with acute tibia and femur fractures were included in this Phase II screening randomized trial comparing the effect of high loading dose Vitamin D3 supplementation (n=27), high daily dose supplementation (n=24), low daily dose supplementation (n=24) and placebo (n=27) on the improvement of fracture healing. Primary outcomes of interest were clinical fracture healing (a...

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