Effect of NSAID Blister Pack on Postoperative Opioid Use
Scheduled, Simultaneous Dosing of Pregabalin, Celecoxib, and Acetaminophen Markedly Reduces or Eliminates Opioid Use After ACL Reconstruction Using Allograft or Hamstring Tendon Autograft: A Randomized Clinical TrialOrthop J Sports Med . 2022 Dec 8;10(12):23259671221140837
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One hundred patients undergoing anterior cruciate ligament reconstruction (ACLR) with either an allograft or hamstring tendon autograft for ACL ruptures were randomized to either a blister pack of non-steroidal anti-inflammatory drugs (NSAIDs; n=50) or ibuprofen and opioids (n=50). Outcomes of interest were nausea, itching, and pain measured using the Verbal Numeric Rating Scale (VNRS) and oxycodo...
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