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Effect of NSAID Blister Pack on Postoperative Opioid Use
February 2023
Effect of NSAID Blister Pack on Postoperative Opioid Use
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Scheduled, Simultaneous Dosing of Pregabalin, Celecoxib, and Acetaminophen Markedly Reduces or Eliminates Opioid Use After ACL Reconstruction Using Allograft or Hamstring Tendon Autograft: A Randomized Clinical Trial
Orthop J Sports Med . 2022 Dec 8;10(12):23259671221140837Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred patients undergoing anterior cruciate ligament reconstruction (ACLR) with either an allograft or hamstring tendon autograft for ACL ruptures were randomized to either a blister pack of non-steroidal anti-inflammatory drugs (NSAIDs; n=50) or ibuprofen and opioids (n=50). Outcomes of interest were nausea, itching, and pain measured using the Verbal Numeric Rating Scale (VNRS) and oxycodo...
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