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Ace Report Cover

Effect of NSAID Blister Pack on Postoperative Opioid Use

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Ace Report Cover
February 2023

Effect of NSAID Blister Pack on Postoperative Opioid Use

Vol: 303| Issue: 2| Number:23| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Scheduled, Simultaneous Dosing of Pregabalin, Celecoxib, and Acetaminophen Markedly Reduces or Eliminates Opioid Use After ACL Reconstruction Using Allograft or Hamstring Tendon Autograft: A Randomized Clinical Trial

Orthop J Sports Med . 2022 Dec 8;10(12):23259671221140837

Contributing Authors:
JD Swenson KM Conrad NL Pace K Phillips CL Saltzman

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Synopsis

One hundred patients undergoing anterior cruciate ligament reconstruction (ACLR) with either an allograft or hamstring tendon autograft for ACL ruptures were randomized to either a blister pack of non-steroidal anti-inflammatory drugs (NSAIDs; n=50) or ibuprofen and opioids (n=50). Outcomes of interest were nausea, itching, and pain measured using the Verbal Numeric Rating Scale (VNRS) and oxycodo...

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