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Vol:255 Issue:3 Number:23 ISSN#:2564-2537
ACE Report #14718
Ace Report Cover Shoulder & Elbow

COA 2022: Efficacy of Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair

How to Cite

OrthoEvidence. COA 2022: Efficacy of Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair. ACE Report. 2022;255(3):23. Available from:

Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy of Liposomal Bupivacaine in Arthroscopic Rotator Cuff Repair: A Meta-Analysis of Randomized Controlled Trials

Contributing Authors:
SI Alaqaili M Al-Saati M Alyousef M Alzayer AS Alsultan MM Alzahrani SM Alqahtani

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


Five RCTs (n=295 patients) were included in this meta-analysis comparing liposomal bupivacaine (n=148) vs. non-liposomal local anesthetic agents (n=147). The main outcomes that were analyzed were the postoperative visual analogue scale (VAS) pain scores and opioid consumption, measured in morphine milligram equivalents (MME). The results showed significant differences in the reduction of VAS pain ...

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