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Ace Report Cover

Adjuvant Topical Tranexamic Acid in Decompressive Spinal Metastasis Surgery

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Ace Report Cover
April 2022

Adjuvant Topical Tranexamic Acid in Decompressive Spinal Metastasis Surgery

Vol: 225| Issue: 1| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Adjunctive Topical Tranexamic Acid for Blood Salvage Does Not Reduce Postoperative Blood Loss Compared with Placebo in Patients Who Undergo Palliative Decompressive Spinal Metastasis Surgery: A Randomized Controlled Trial

Spine (Phila Pa 1976) . 2022 Feb 1;47(3):187-194.

Contributing Authors:
R Maethungkul P Atthakomol P Phinyo A Phanphaisarn H Murakami A Sangsin

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Synopsis

Sixty five patients undergoing decompressive thoracolumbar spinal metastasis surgery were randomized to receive topical intraoperative tranexamic acid (TXA, n=33) or placebo (n=32). All patients received perioperative IV TXA. The primary outcomes of interest were intraoperative and postoperative blood loss, transfusion rates and overall complications. There was no difference in blood loss or trans...

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