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Efficacy and Safety of Tranexamic Acid in Hip Fracture Surgery
March 2022
Efficacy and Safety of Tranexamic Acid in Hip Fracture Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials
Injury. 2022 Feb;53(2): 294-300.Synopsis
A meta-analysis of 10 randomized controlled trials (n=1123) undergoing hip fracture surgery with patients randomized to receive perioperative intravenous TXA (n=557) or a control group (n=566) was performed. The primary outcome of interest was total blood loss. Secondary outcomes of interest included transfusion rates and incidence of thromboembolic events. The TXA group demonstrated significantly...
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