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Vol:213 Issue:1 Number:2 ISSN#:2564-2537
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Meta-Analysis
ACE Report #14422
Ace Report Cover Trauma

Efficacy and Safety of Tranexamic Acid in Hip Fracture Surgery


How to Cite

OrthoEvidence. Efficacy and Safety of Tranexamic Acid in Hip Fracture Surgery. ACE Report. 2022;213(1):2. Available from: https://myorthoevidence.com/AceReport/Report/14422

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials

Injury. 2022 Feb;53(2): 294-300.

Contributing Authors:
P Masouros G Antoniou VS Nikolaou

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Synopsis

A meta-analysis of 10 randomized controlled trials (n=1123) undergoing hip fracture surgery with patients randomized to receive perioperative intravenous TXA (n=557) or a control group (n=566) was performed. The primary outcome of interest was total blood loss. Secondary outcomes of interest included transfusion rates and incidence of thromboembolic events. The TXA group demonstrated significantly...

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