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Volume:131 Issue:1 Number:3 ISSN#:2564-2537
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RCT
ACE Report #14083
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Topical Tranexamic Acid After Wound Incision in Acute Thoracolumbar Burst Fracture Surgery


How to Cite

OrthoEvidence. Topical Tranexamic Acid After Wound Incision in Acute Thoracolumbar Burst Fracture Surgery. ACE Report. 2021;131(1):3. Available from: https://myorthoevidence.com/AceReport/Report/14083

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

The influence of topical use of tranexamic acid in reducing blood loss on early operation for thoracolumbar burst fracture: a randomized double-blinded controlled study

Eur Spine J. 2021 Oct;30(10): 3074-3080.

Contributing Authors: J Shen Z Yang M Fu J Hao W Jiang

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Synopsis

Ninety-three patients with acute thoracolumbar burst fractures scheduled for an open decompression, fracture reduction and internal fixation procedure were randomized to receive topical tranexamic acid (n=46) or normal saline (n=47) after wound incision for the reduction of blood loss. Outcomes of interest included blood loss (intra-operative, post-operative, total, hidden), operative time, hemogl...

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