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Platelet-Rich Plasma vs Sham Injection on Tendon Dysfunction in Patients With Achilles Tendinopathy

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Ace Report Cover
March 2025

Platelet-Rich Plasma vs Sham Injection on Tendon Dysfunction in Patients With Achilles Tendinopathy

Vol: 307| Issue: 3| Number:108| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy: A Randomized Clinical Trial.

JAMA. 2021 13-Jul;():. 10.1177/0269215521989016.

Contributing Authors:
RS Kearney C Ji J Warwick N Parsons J Brown P Harrison J Young ML Costa

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Synopsis

Two hundred forty patients with chronic midportion Achilles tendinopathy were randomized to receive either a single platelet-rich plasma (PRP) injection (n=121) or a sham subcutaneous dry needle injection (n=119). The primary outcome was the VISA-A score at 6 months, which assesses pain, function, and activity limitations related to Achilles tendinopathy. Secondary outcomes included the VISA-A sco...

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