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Volume:103 Issue:1 Number:1 ISSN#:2564-2537
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RCT
ACE Report #13943
Ace Report Cover Osteoarthritis

Tranexamic Acid Reduces Blood Loss After High Tibial Osteotomy for Knee Osteoarthritis


How to Cite

OrthoEvidence. Tranexamic Acid Reduces Blood Loss After High Tibial Osteotomy for Knee Osteoarthritis. ACE Report. 2021;103(1):1. Available from: https://myorthoevidence.com/AceReport/Report/13943

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Tranexamic acid is beneficial for blood management of high tibial osteotomy: a randomized controlled study.

Arch Orthop Trauma Surg. 2021 Sep;141(9): 1463-1472.

Contributing Authors: J Ni J Liu J Zhang J Jiang X Dang Z Shi

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Synopsis

One hundred patients with medial compartment knee osteoarthritis with varus deformity scheduled to undergo a high tibial osteotomy were randomized to receive intravenous tranexamic acid (TXA; n=50) or control (normal saline; n=50) for the management of blood loss. Outcomes of interest included drainage volume, blood loss, hemoglobin and hematocrit levels, and adverse events. Results revealed signi...

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