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Cryoneurolysis Before Total Knee Arthroplasty in Severe Osteoarthritis Patients for Post-op Pain

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Ace Report Cover
February 2022

Cryoneurolysis Before Total Knee Arthroplasty in Severe Osteoarthritis Patients for Post-op Pain

Vol: 189| Issue: 1| Number:1| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Cryoneurolysis before Total Knee Arthroplasty in Patients With Severe Osteoarthritis for Reduction of Postoperative Pain and Opioid Use in a Single-Center Randomized Controlled Trial

J Arthroplasty. 2021 May;36(5): 1590-1598.

Contributing Authors:
WM Mihalko AL Kerkhof MC Ford Jr Crockarell JR JW Harkess JL Guyton

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Synopsis

One hundred and sixty-four patients with severe knee osteoarthritis scheduled for a total knee arthroplasty were randomized to receive pre-operative cryoneurolysis plus standard of care pain management (n=62) or standard of care pain management only (n=62). The primary endpoint was cumulative opioid consumption. Secondary endpoints included improvement in Numeric Rating Scale (NRS) pain scores and...

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