Oral Prednisone Reduces Pain & Analgesic Consumption Up to 1 Month Post-Surgery in TKA Patients

How to Cite

OrthoEvidence. Oral Prednisone Reduces Pain & Analgesic Consumption Up to 1 Month Post-Surgery in TKA Patients. ACE Report. 2021;47(1):4. Available from: https://myorthoevidence.com/AceReport/Report/13675

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Oral administration of prednisone effectively reduces subacute pain after total knee arthroplasty

Orthop Traumatol Surg Res. 2021 May;107(3): 102770.

Contributing Authors: X Cheng Z Wang Y Zhang X Zhang

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

One hundred patients scheduled to undergo a primary total knee arthroplasty (TKA) were randomized to receive 2 weeks of daily 10 mg oral prednisone (n=50) or control (n=50) for post-surgical pain relief. Primary outcomes of interest included pain during rest and movement measured using the visual analogue scale (VAS), which were both evaluated up to 84 days post-TKA. Secondary outcomes of interest...