Bone Morphogenetic Protein-2 vs Iliac Crest Bone Grafting for Posterolateral Lumbar Spine Fusion

How to Cite

OrthoEvidence. Bone Morphogenetic Protein-2 vs Iliac Crest Bone Grafting for Posterolateral Lumbar Spine Fusion. ACE Report. 2021;45(1):1. Available from: https://myorthoevidence.com/AceReport/Report/13649

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Bone morphogenetic protein-2 against iliac crest bone graft for the posterolateral fusion of the lumbar spine: A meta-analysis

Int J Clin Pract. 2021 Apr;75(4): e13911.

Contributing Authors: Z Wu B Zhou L Chen X Wang MEA Abdelrahim C Wei

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

Fourteen studies with a total of 1516 patients undergoing posterolateral lumbar spine fusion were included in this meta-analysis comparing iliac crest bone grafting (n=727) to bone morphogenetic protein-2 (n=789). Pooled outcomes of interest included the rate of fusion, rate of non-union, operative time, blood loss, length of stay, need for secondary surgery, Oswestry Disability Index (ODI) scores...