Ramelteon Ineffective in Preventing Post-Op Delirium in Patients Undergoing Joint Replacement
How to Cite
OrthoEvidence. Ramelteon Ineffective in Preventing Post-Op Delirium in Patients Undergoing Joint Replacement. ACE Report. 2021;10(3):2. Available from: https://myorthoevidene.com/AceReport/Report/13120
Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled TrialAm J Geriatr Psychiatry. 2021 Jan;29(1):90-100.
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Eighty patients scheduled for a hip or knee replacement surgery were randomized to receive oral ramelteon (n=41) or placebo (n=39) for the prevention of post-operative delirium. The primary outcome of interest was the incidence of delirium during post-operative day 0 and post-operative day 1-2, as measured by the Aldrete score. Secondary outcomes included the Delirium Rating Scale Revised 98 (DRS-...
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