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100 mg Aspirin Twice Daily Non-Inferior to Once Daily 10 mg Rivaroxaban for Prevention of VTE in THA
February 2021
100 mg Aspirin Twice Daily Non-Inferior to Once Daily 10 mg Rivaroxaban for Prevention of VTE in THA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparable efficacy of 100 mg aspirin twice daily and rivaroxaban for venous thromboembolism prophylaxis following primary total hip arthroplasty: a randomized controlled trial
Chin Med J (Engl). 2021 Jan 5;134(2):164-172.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy-eight patients undergoing a unilateral total hip arthroplasty (THA) were randomized in this non-inferiority trial to receive 5 weeks of aspirin (100 mg twice per day; n=37) or 5 weeks of rivaroxaban (10 mg once per day) post-operation for the prevention of deep vein thrombosis (DVT). The primary outcome of interest was the incidence of DVT which was assessed using Doppler ultrasonography a...
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