100 mg Aspirin Twice Daily Non-Inferior to Once Daily 10 mg Rivaroxaban for Prevention of VTE in THA

How to Cite

OrthoEvidence. 100 mg Aspirin Twice Daily Non-Inferior to Once Daily 10 mg Rivaroxaban for Prevention of VTE in THA. ACE Report. 2021;10(2):36. Available from: https://myorthoevidene.com/AceReport/Report/13116

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Comparable efficacy of 100 mg aspirin twice daily and rivaroxaban for venous thromboembolism prophylaxis following primary total hip arthroplasty: a randomized controlled trial

Chin Med J (Engl). 2021 Jan 5;134(2):164-172.

Contributing Authors: Y Ren SL Cao Z Li T Luo B Feng XS Weng

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Synopsis

Seventy-eight patients undergoing a unilateral total hip arthroplasty (THA) were randomized in this non-inferiority trial to receive 5 weeks of aspirin (100 mg twice per day; n=37) or 5 weeks of rivaroxaban (10 mg once per day) post-operation for the prevention of deep vein thrombosis (DVT). The primary outcome of interest was the incidence of DVT which was assessed using Doppler ultrasonography a...