PRP Injection Improves Pain, Function & Quality of Life vs HA Injection for Knee Osteoarthritis

How to Cite

OrthoEvidence. PRP Injection Improves Pain, Function & Quality of Life vs HA Injection for Knee Osteoarthritis. ACE Report. 2021;10(1):43. Available from: https://myorthoevidene.com/AceReport/Report/13054

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Platelet-Rich Plasma Versus Hyaluronic Acid in the Treatment of Knee Osteoarthritis: A Meta-analysis of 26 Randomized Controlled Trials

Arthroscopy. 2021 Jan;37(1):309-325.

Contributing Authors: J Tan H Chen L Zhao W Huang

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Synopsis

Twenty-six randomized controlled trials including 2430 adults with knee osteoarthritis (OA) were included in this meta-analysis comparing platelet-rich plasma (PRP) injections and hyaluronic acid (HA) injections for the relief of symptoms. Pooled outcomes of interest included the incidence of adverse events, the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index, pain, stiffnes...