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Superior Clinical Improvement with Cooled Radiofrequency Ablation vs HA Injection for Knee OA Pain

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Ace Report Cover
January 2021

Superior Clinical Improvement with Cooled Radiofrequency Ablation vs HA Injection for Knee OA Pain

Vol: 10| Issue: 1| Number:9| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Cooled Radiofrequency Ablation Compared with a Single Injection of Hyaluronic Acid for Chronic Knee Pain: A Multicenter, Randomized Clinical Trial Demonstrating Greater Efficacy and Equivalent Safety for Cooled Radiofrequency Ablation.

J Bone Joint Surg Am. 2020 Sep 2;102(17):1501-1510.

Contributing Authors:
AF Chen F Khalouf K Zora M DePalma L Kohan M Guirguis D Beall E Loudermilk M Pingree I Badiola J Lyman

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Synopsis

One hundred and seventy-seven patients with chronic knee pain from knee osteoarthritis (OA) were randomized to receive cooled radiofrequency ablation (CRFA; n=89) of the genicular nerves or a single intra-articular hyaluronic acid (HA; n=88). The primary outcome of interest was the number of patients who reported a =>50% reduction in pain scores from baseline after 6 months. Additional outcomes of...

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