Superior Clinical Improvement with Cooled Radiofrequency Ablation vs HA Injection for Knee OA Pain

How to Cite

OrthoEvidence. Superior Clinical Improvement with Cooled Radiofrequency Ablation vs HA Injection for Knee OA Pain. ACE Report. 2021;10(1):9. Available from: https://myorthoevidene.com/AceReport/Report/12871

Study Type:Therapy

OE Level Evidence:1

Journal Level of Evidence:1

Cooled Radiofrequency Ablation Compared with a Single Injection of Hyaluronic Acid for Chronic Knee Pain: A Multicenter, Randomized Clinical Trial Demonstrating Greater Efficacy and Equivalent Safety for Cooled Radiofrequency Ablation.

J Bone Joint Surg Am. 2020 Sep 2;102(17):1501-1510.

Contributing Authors: AF Chen F Khalouf K Zora M DePalma L Kohan M Guirguis D Beall E Loudermilk M Pingree I Badiola J Lyman

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Synopsis

One hundred and seventy-seven patients with chronic knee pain from knee osteoarthritis (OA) were randomized to receive cooled radiofrequency ablation (CRFA; n=89) of the genicular nerves or a single intra-articular hyaluronic acid (HA; n=88). The primary outcome of interest was the number of patients who reported a =>50% reduction in pain scores from baseline after 6 months. Additional outcomes of...