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Volume:9 Issue:10 Number:26 ISSN#:2563-5476
ACE Report #12479
Ace Report Cover General Orthopaedics

OTA 2020: Vitamin D3 Supplementation Does Not Improve Tibia/Femur Fracture Healing

How to Cite

OrthoEvidence. OTA 2020: Vitamin D3 Supplementation Does Not Improve Tibia/Femur Fracture Healing. ACE Report. 2020;9(10):26. Available from: https://myorthoevidene.com/AceReport/Report/12479

Study Type:N/A
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Vitamin D3 Supplementation DOes Not Improve Fracture Healing: A Double-blinded Randomized Controlled Trial

Contributing Authors: G Slobogean D Connelly S Sprague S Bzovsky Z Hannan J Adachi The Vita-Shock Investigators

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


A total of 101 patients aged 18 to 55 years old with a tibia or femoral shaft fracture receiving intramedullary nailing for fracture fixation were randomized to receive vitamin D3 supplementation of 150,000 IU at injury and 6 weeks, 4000 IU/day for 3 months, 600 IU/day for 3 months, or the placebo. The primary outcomes of interest were radiographic healing scores (Radiographic Union Scale in Tibia...

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