
Oral pregabalin ineffective for pain reduction after posterior spinal fusion surgery in adolescents

Oral pregabalin ineffective for pain reduction after posterior spinal fusion surgery in adolescents
Preemptive Pregabalin in Children and Adolescents Undergoing Posterior Instrumented Spinal Fusion: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial.
J Bone Joint Surg Am. 2020 Feb 5;102(3):205-212.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Sixty-four adolescent patients scheduled for a posterior spinal fusion surgery were randomized to receive peri-operative oral pregabalin or placebo for the reduction of pain and opioid consumption post-operation. The primary outcomes of interest were oxycodone cumulative consumption and oxycodone consumption rate. Secondary outcomes of interest included pain scores on the Scoliosis Research Societ...
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