ACE Report #12030
Ace Report Cover Arthroplasty

Efficacy of IV, intraarticular and epidural ketamine for post-op pain after total joint arthroplasty

Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Analgesic efficacy and safety of ketamine after total knee or hip arthroplasty: a meta-analysis of randomised placebo-controlled studies

BMJ Open. 2019 Sep 13;9(9):e028337.

Contributing Authors: B Xu Y Wang C Zeng J Wei J Li Z Wu H He G Lei D Xie X Ding

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Ten studies were included in this meta-analysis comparing varying routes of administration of ketamine to placebo in patients undergoing total joint arthroplasty (TJA). The primary outcome of interest was pain intensity. Secondary outcomes of interest included cumulative morphine consumption and the incidence of adverse events. Results of the meta-analysis found significantly lower early post-oper...

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