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RCT
ACE Report #11994
Ace Report Cover General Orthopaedics

TMR in Major Limb Amputees Reduces Phantom Limb Pain vs. Standard Neuroma Treatment


Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

Targeted Muscle Reinnervation Treats Neuroma and Phantom Pain in Major Limb Amputees: A Randomized Clinical Trial

Ann Surg. 2019 Aug;270(2):238-246.

Contributing Authors: GA Dumanian BK Potter LM Mioton JH Ko JE Cheesborough JM Souza WJ Ertl SM Tintle GP Nanos IL Valerio TA Kuiken AV Apkarian K Porter SW Jordan

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Synopsis

28 patients (30 limbs) were included in this study comparing Targeted Muscle Re-innervation (TMR) and a standard surgical treatment involving neuroma excision and burial into nearby muscle in patients with major limb amputations above the wrist or ankle. The primary outcomes of interest were the worst residual limb pain and phantom limb pain, measured using a numerical rating scale (NRS). Secondar...

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