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Favourable pain relief, less opioid-related AEs with LIA vs. intrathecal morphine after TKR surgery
August 2019
Favourable pain relief, less opioid-related AEs with LIA vs. intrathecal morphine after TKR surgery
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A
A comparison of the analgesic efficacy of local infiltration analgesia vs. intrathecal morphine after total knee replacement: A randomised controlled trial
Eur J Anaesthesiol. 2019 Apr;36(4):264-271.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
53 patients scheduled for a unilateral total knee replacement under spinal anesthesia were randomized to receive local infiltration analgesia with levobupivacaine and adrenaline, or intrathecal preservative-free morphine in conjunction with the spinal anesthesia. The primary outcomes of interest were pain scores at 24 hours at rest and on passive flexion to 30deg, measured on a Visual Analog Scale...
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