Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
Meta-analysis
ACE Report #11839
Ace Report Cover General Orthopaedics

COA/ICORS2019: NSAID use >4wks, especially indomethacin, associated with non-union in bone fractures


Study Type:Meta analysis
OE Level Evidence:N/A
Journal Level of Evidence:N/A

The Effect of NSAIDs on Post-Fracture Bone Healing; A Meta-Analysis of Randomized Controlled Trials

Contributing Authors: H Al Farii L Farahdel A Salimi

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

6 RCTs (609 patients) were included in this meta-analysis which examined the risk of nonunion after fracture in patients taking non-steroidal anti-inflammatory drugs (NSAIDs). The primary outcome of interest was nonunion, and the relative risk based on duration of use and type of NSAID was analyzed via a regression analysis. The results revealed that NSAID use longer than 4 weeks resulted in a sig...

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.

LEARN MORE

Please Login or Join to leave comments.