Tranexamic acid reduces blood loss in corrective surgery for adolescent idiopathic scoliosis
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled TrialJ Bone Joint Surg Am. 2018 Dec 5;100(23):2024-2032
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120 patients, 10-18 years of age, scheduled for corrective instrumented posterior fusion for adolescent scoliosis were randomized to either intravenous tranexamic acid or placebo. Patients were assessed for blood loss parameters intraoperatively and over the first 24 hours postoperatively. Results demonstrated a significantly lower rate of clinically relevant blood loss, defined as >20mL/kg, in th...
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