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Tranexamic acid reduces blood loss in corrective surgery for adolescent idiopathic scoliosis
March 2019
Tranexamic acid reduces blood loss in corrective surgery for adolescent idiopathic scoliosis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial
J Bone Joint Surg Am. 2018 Dec 5;100(23):2024-2032Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
120 patients, 10-18 years of age, scheduled for corrective instrumented posterior fusion for adolescent scoliosis were randomized to either intravenous tranexamic acid or placebo. Patients were assessed for blood loss parameters intraoperatively and over the first 24 hours postoperatively. Results demonstrated a significantly lower rate of clinically relevant blood loss, defined as >20mL/kg, in th...
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