Titrated THC and CBD does not significantly improve spasticity compared to placebo over 4 weeks
Sativex and clinical-neurophysiological measures of spasticity in progressive multiple sclerosisJ Neurol. 2015 Nov;262(11):2520-7
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34 patients with progressive multiple sclerosis were treated with titrated doses of Sativex (9-delta-tetrahydrocannabinol and cannabidiol oromucosal spray) or placebo in a randomly assigned order for 4 weeks each. The purpose of the study was to determine if of 9-delta-tetrahydrocannabinol and cannabidiol treatment significantly improves neurophysiological and clinical measures of spasticity, pain...
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