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Titrated THC and CBD does not significantly improve spasticity compared to placebo over 4 weeks
January 2019
Titrated THC and CBD does not significantly improve spasticity compared to placebo over 4 weeks
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Sativex and clinical-neurophysiological measures of spasticity in progressive multiple sclerosis
J Neurol. 2015 Nov;262(11):2520-7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
34 patients with progressive multiple sclerosis were treated with titrated doses of Sativex (9-delta-tetrahydrocannabinol and cannabidiol oromucosal spray) or placebo in a randomly assigned order for 4 weeks each. The purpose of the study was to determine if of 9-delta-tetrahydrocannabinol and cannabidiol treatment significantly improves neurophysiological and clinical measures of spasticity, pain...
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