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Pre- versus perioperative intravenous dexamethasone for analgesia in total knee arthroplasty
December 2018
Pre- versus perioperative intravenous dexamethasone for analgesia in total knee arthroplasty
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A
Multiple Doses of Perioperative Dexamethasone Further Improve Clinical Outcomes After Total Knee Arthroplasty: A Prospective, Randomized, Controlled Study
J Arthroplasty. 2018 Nov;33(11):3448-3454. doi: 10.1016/j.arth.2018.06.031Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
182 patients scheduled for total knee arthroplasty were randomized to either perioperative intravenous dexamethasone administration, including one dose preoperative and subsequent doses at 24 and 48 hours afterward, to a single preoperative intravenous dexamethasone infusion, or to no dexamethasone administration. Patients were assessed for pain scores, analgesic consumption, incidence of postope...
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