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Intraarticular stem cell injection favoured over oral acetaminophen after 6-mo in knee OA treatment

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Ace Report Cover
May 2019

Intraarticular stem cell injection favoured over oral acetaminophen after 6-mo in knee OA treatment

Vol: 8| Issue: 5| Number:15| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The effect of intra-articular injection of autologous bone marrow stem cells on pain and knee function in patients with osteoarthritis

Int J Rheum Dis. 2018 Jan;21(1):140-147. doi: 10.1111/1756-185X.13139

Contributing Authors:
D Garay-Mendoza L Villarreal-Martinez A Garza-Bedolla Dm Perez-Garza C Acosta-Olivo F Vilchez-Cavazos C Diaz-Hutchinson D Gomez-Almaguer Jc Jaime-Perez C Mancias-Guerra

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Synopsis

61 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to treatment with either a single intraarticular injection of bone morrow-derived mesenchymal stem cells (BM-MSC) or oral acetaminophen 500mg every 8 hours for 6 months. Patients were assessed for outcome on a visual analog scale for pain and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC...

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