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ACE Report #10704
Ace Report Cover Hand & Wrist

Nonopioid analgesics demonstrate similar efficacy to oxycodone following carpal tunnel release

Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:2

Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone

J Hand Surg Am. 2018 Oct;43(10):913-919. doi: 10.1016/j.jhsa.2018.08.011

Contributing Authors: AM Ilyas AJ Miller JL Matzon JG Graham

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110 patients scheduled for miniopen or endoscopic carpal tunnel release were randomized to postoperative analgesia with 10 pills of either acetaminophen 500mg, ibuprofen 600mg, or oxycodone 5mg. Patients were assessed for the mean number of pills consumed and mean pain scores over the first 5 postoperative days, as well as subjective assessment of whether allocated analgesia was adequate, if alloc...

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