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Volume:7 Issue:10 Number:72 ISSN#:2563-5476
ACE Report #10642
Ace Report Cover Trauma

OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

How to Cite

OrthoEvidence. OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis. ACE Report. 2018;7(10):72. Available from: https://myorthoevidene.com/AceReport/Report/10642

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Bleeding Events After Orthopaedic Trauma With Aspirin to Low Molecular Weight Heparin Venous Thromboembolism Prophylaxis

Contributing Authors: G Slobogean RV O'Toole T Manson NN O'Hara B Haac R van Besien D Stein H Johal R Castillo P Berger B Reahl D Marinos Y Degain D Mascarenhas D Connelly T Scalea

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


329 patients with an operative extremity fracture, or pelvic and/or acetabular fracture and required thromboprophylaxis were randomized to either low molecular weight heparin 30mg twice daily or aspirin 81mg twice daily for 90 days. Patients were followed up for bleeding events and venous thromboembolic complications. Results demonstrated no significant differences between groups in rates of eithe...

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