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Increasing number of IV TXA doses further improves efficacy without increasing VTE risk in THA
January 2019
Increasing number of IV TXA doses further improves efficacy without increasing VTE risk in THA
Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A
Multiple-Dose Intravenous Tranexamic Acid Further Reduces Hidden Blood Loss After Total Hip Arthroplasty: A Randomized Controlled Trial
J Arthroplasty. 2018 Sep;33(9):2940-2945. doi: 10.1016/j.arth.2018.04.024Synopsis
150 patients scheduled for total hip arthroplasty and administered an intravenous dose of tranexamic acid prior to incision were randomized to either an additional 2, 3, or 4 IV TXA doses after 3 hour intervals thereafter. Patients were assessed for hidden blood loss, total blood loss, intraoperative blood loss, hemoglobin drop, transfusion rate, length of hospital stay, and incidence of thromboem...
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