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No clear benefit of liposomal bupivacaine over plain bupivacaine for periarticular injection in TKA
October 2018
No clear benefit of liposomal bupivacaine over plain bupivacaine for periarticular injection in TKA
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A
Liposomal Bupivacaine vs Plain Bupivacaine in Periarticular Injection for Control of Pain and Early Motion in Total Knee Arthroplasty: A Randomized, Prospective Study
J Arthroplasty. 2018 Aug;33(8):2460-2464 doi: 10.1016/j.arth.2018.03.014Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
80 patients scheduled for total knee arthroplasty were randomized to periarticular infiltration analgesia completed using either liposomal bupivacaine or plain bupivacaine. Outcomes of interest included pain scores during physical therapy, narcotic consumption, and knee range of motion. Assessment timepoints included 24 hours, 48 hours, 72 hours, and at discharge. While pain scores during physical...
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