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Delta-9 THC Improves Pain and Spasticity Compared to Placebo for Multiple Sclerosis Over 2 Weeks

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Ace Report Cover
August 2018

Delta-9 THC Improves Pain and Spasticity Compared to Placebo for Multiple Sclerosis Over 2 Weeks

Vol: 7| Issue: 8| Number:18| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial

CMAJ. 2012 Jul 10;184(10):1143-50. https://dx.doi.org/10.1503/cmaj.110837

Contributing Authors:
S Jin B Gouaux TD Marcotte H Bentley T Wolfson A Gamst J Corey-Bloom

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Synopsis

30 patients with multiple sclerosis smoked 800 mg cannabis cigarettes containing 4% delta-9 tetrahydrocannabinol (delta-9 THC) or placebo in a randomized order for 2 weeks each. The purpose of this study was to determine if cannabis improved pain and spasticity while maintaining similar effects on cognition, deficits, fatigue, mood, movement, and symptoms as placebo. Results indicated that cannabi...

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