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Volume:7 Issue:10 Number:9 ISSN#:2563-5476
RCT
ACE Report #10380
Ace Report Cover Cannabis

Nabilone reduces pain and improves sleep and quality of life in diabetic peripheral neuropathic pain


How to Cite

OrthoEvidence. Nabilone reduces pain and improves sleep and quality of life in diabetic peripheral neuropathic pain. ACE Report. 2018;7(10):9. Available from: https://myorthoevidene.com/AceReport/Report/10380

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo-controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain

Pain. 2012 Oct;153(10):2073-82. https://dx.doi.org/10.1016/j.pain.2012.06.024

Contributing Authors: C Liu A Garven C Toth S Mawani S Brady C Chan E Mehina J Bestard L Korngut

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Synopsis

26 adults with diabetic neuropathic pain were randomized to receive either oral nabilone (a synthetic cannabinoid) or placebo for 5 weeks. The primary outcome was the average daily pain score, and secondary outcomes included sleep, anxiety, depression, treatment satisfaction, and quality of life. Results demonstrated that nabilone was more effective than placebo for reducing pain, improving sleep...

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